Job Opportunities with Nitto Denko Avecia in the USA
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Why work at Avecia?

As a leading drug development services company for oligonucleotide therapeutics, the first step in our DNA/RNA sequence is to work with a great team of people.

At Avecia, our team approach allows you to excel in your individual area of expertise as well as to be part of a group of professionals that has the support of management and peers from various backgrounds. And while we’re focused on results, we still maintain our flexibility and enjoy camaraderie and the benefits of work/life balance. Make the next move in your progression of success and join Avecia.

At Avecia, we encourage and value people from diverse ethnic and cultural backgrounds to contribute to our collective success. It is Avecia’s policy to conduct business without regard to an individual’s disability or any other protected status. We are fully committed to the concept and practice of equal opportunity and affirmative action in all aspects of employment and encourage all to apply.

AD Associate Scientist

Department: Analytical Method Development
Location: Cincinnati, OH

Purpose of the Position:

  • This posting is for an Associate Scientist position in a pharmaceutical Analytical Development Laboratory that follows GMP guidelines. The focus of this position would be development of mass spectrometry techniques for micro RNAs and various oligonucleotides (includes enzyme digestions and sequencing). In addition, the responsibilities include development of electrophoresis, blotting, Capillary Electrophoresis (CE) and UPLC for microRNA testing.

    Key Job Responsibilities:

  • Develop LC-MS and sequencing approaches determining microRNAs.

  • Contribute to the development and establishment of electrophoresis, blotting, CE and UPLC for microRNA testing

  • Performing sequencing of oligonucleotides using ESI-MS/MS approach.

  • Performs mass spectrometry characterization of impurity profiles.

  • Develop separations for the analysis of oligonucleotides using ion-pair chromatography, anion exchange chromatography and size exclusion chromatography.

  • Validate release methods for active pharmaceutical ingredients.

  • Use analytical skills to support oligonucleotide manufacturing group.

  • Participate in client site visits, teleconferences and audits.

  • Maintain accurate and complete lab notebooks.

  • Write analytical laboratory SOPs, protocols and compliance documents.

  • Responsible for laboratory investigations, troubleshooting of analytical problems, and technology transfer of analytical methods for new and existing drug substance to other laboratories.

  • Participate in cGMP training, implement cGMP operating procedures.

  • Participates and contributes to safety programs, performs instrument audits, and maintains and orderly and safe laboratory environment.

  • Review laboratory documentation for calculation, entry and cGMP compliance.

  • Solve complex, non-routing analytical and protocol problems independently.

  • Develops and modifies test methods.

  • Train BS/MS and technician level chemists and analysts.

    Job Knowledge Required:

  • PhD and 0-2 years of experience or MS and 5-7 years of experience with concentration in Analytical Chemistry and analysis of macromolecules such as oligonucleotides or peptides

  • High level of knowledge in mass spectrometry (LC-MS, enzyme digestions, ESI-MS/MS sequencing)

  • High level of knowledge in separation techniques (UPLC and HPLC)

  • Knowledgeable in the cGMP area is a plus

  • Any experience in microRNAs and long oligonucleotides > 50 resides is a plus

  • Very strong oral and written communication skills


  • Employee is responsible for on time performance and documenting accomplishments associated with the job function.
  • Tasks are performed with the minimum supervision.
  • Employee must be able to directly interact with various functional groups.
  • Documentation of work must be compliant with Good Documentation Practices and Good Manufacturing Practices.

Equal Opportunity Employer

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